What Is SPRAVATO®?

SPRAVATO® (esketamine) is an FDA-approved nasal spray derived from ketamine, designed specifically for treatment-resistant depression and major depressive disorder with suicidal thoughts or behaviors. Unlike traditional antidepressants, SPRAVATO® works on the NMDA receptor in the brain and often produces faster results when combined with oral antidepressants.

At Restore Compassionate Care, SPRAVATO® is administered in a safe, controlled environment under close supervision by trained medical professionals.


Conditions Treated

SPRAVATO® is currently approved to treat:

  • Treatment-Resistant Depression (TRD)
    (Depression that hasn’t responded to at least two other antidepressants)
  • Major Depressive Disorder (MDD) with acute suicidal ideation or behavior
    (For clients needing rapid symptom relief in crisis situations)

Who It’s For

SPRAVATO® may be a good fit if you:

  • Have tried multiple antidepressants with little or no improvement
  • Experience significant side effects from oral medications
  • Need fast-acting relief for depressive symptoms
  • Are under psychiatric care and looking for additional support options

Note: SPRAVATO® is not a first-line treatment and is prescribed only after a thorough psychiatric evaluation and medical screening. It is not recommended for individuals with certain medical conditions or a history of substance misuse.


Appointment & Insurance Information

SPRAVATO® must be administered in person at our office, as required by the REMS (Risk Evaluation and Mitigation Strategy) program. Sessions typically occur 2 times per week for the first 4 weeks, followed by tapering sessions over the next 8 weeks and beyond.

What to expect:

  • You’ll self-administer the nasal spray in a quiet, monitored room
  • Sessions last approximately 2 hours, including observation time
  • You will need a ride home—you cannot drive until the next day

Insurance & Cost:

  • We work with major insurance providers to determine eligibility and prior authorizations
  • Out-of-pocket costs vary depending on coverage
  • Our team can help you understand your benefits and coordinate coverage with Janssen’s SPRAVATO® Support Program

Interested in SPRAVATO®?

We’re here to answer your questions and help you determine whether SPRAVATO® is right for you.

Contact us to take the next step.